Spravato® for Treatment-Resistant Depression

Structured. Supervised. Clinically Intentional.

When depression doesn’t respond to standard treatment, the answer isn’t more of the same.
Spravato® offers a clinically different option—delivered with precision, medical oversight,

and clear goals.

At Mercurius Psychiatry, Spravato® is not treated as a last resort.
It’s treated as a focused, evidence-based pathway for patients who need a different mechanism of care.

What Is Spravato®?

Spravato® (esketamine) is an FDA-approved treatment for treatment-resistant depression and certain cases of major depressive disorder.

Unlike traditional antidepressants that work gradually through serotonin pathways, Spravato® acts on NMDA receptors, influencing glutamate activity in the brain—an area strongly linked to mood regulation, neuroplasticity, and emotional processing.

This difference matters when other treatments haven’t worked.

FDA-Certified Spravato® Provider

Mercurius Psychiatry is an FDA-certified Spravato® provider, which means:

Treatment is delivered on-site

Dosing follows strict clinical protocols

Each session includes medical supervision

Ongoing psychiatric follow-up is built into care

Spravato® is not prescribed casually.
It is administered with intention, structure, and accountability.

Who Spravato® May Be For

Spravato® may be appropriate if you:

Have tried multiple antidepressants without adequate relief

Experience persistent depression despite consistent treatment

Need an option beyond medication adjustments alone

Require a more biologically targeted intervention

Eligibility is determined through clinical screening, not assumptions.

How Spravato® Treatment Works

Spravato® treatment at Mercurius Psychiatry includes:

  • Comprehensive Evaluation: A full psychiatric assessment to determine clinical appropriateness.

  • Required Monitoring Period: Patients are observed after each session to ensure safety and stability.

  • On-Site Administration: Spravato® is self-administered under medical supervision in a controlled setting.

  • Ongoing Psychiatric Oversight: Treatment progress is monitored, adjusted, and reviewed—not left on autopilot.

Why Delivery Matters:

Spravato® isn’t just about the medication—it’s about how it’s delivered.

At Mercurius Psychiatry:

Oversight is continuous

Screening is thorough

Follow-up is intentional

Education Is Part of Care

We believe patients deserve to understand:

What Spravato® does

Why it works differently

What realistic outcomes look like

Education isn’t extra—it’s essential.
Informed patients make stronger, more sustainable progress.

A Different Approach—Before It’s Too Late

Spravato® is often discovered after years of trial and error.
It doesn’t have to be.

If standard treatments haven’t brought relief, exploring a different clinical pathway sooner—not later—can change the trajectory.

Proudly Serving Fellow Veterans

Proudly Serving Fellow Veterans

P: (603) 441-2336
F: (603) 316-5540

15 Forest Road,
HANCOCK, NH 03449

[email protected]